COMFA (Computer-assisted Molecular Field Analysis) -
Utilized results of cyclic AMP and receptor binding assays in conjunction with SYBIL software to predict binding site characteristics of dopamine and serotonin receptors. |
Drug Discrimination -
Trained and maintained rats to discriminate ethanol from saline. Assessed the similarity of neurosteroids to the discriminative effects of ethanol as well as possible antagonism. |
Electrophysiology -
Utilized Xenopus oocyte whole cell clamping to measure ion flow through expressed CFTR chloride channel constructs. |
GC -
Ran rodent breath samples on a gas chromatograph to separate and quantify ethanol. |
HPLC -
Constructed and maintained high performance liquid chromatography systems (BAS, inc. and ESA, inc.) utilizing electrochemical detection of monoamine neurotransmitters. |
Molecular Biology -
Constructed mutant CFTR chloride channels and expressed constructs in Xenopus oocytes. |
Motor Behavior -
Utilized open-field locomotor behavior, as well as ataxia on an inverted screen, catalepsy on a raised bar, and loss of righting reflex to assess drug effects in mice. |
Mouse Breathalyzer -
Developed an assay to sample and analyze breath ethanol levels in the mouse. Involved in restraint design, training, and assay validation. |
Operant Behavior -
Trained and maintained mice, rats, pigeons, and non-human primates on drug (ethanol, cocaine), shock, and food reinforced operant behaviors. Schedules utilized include fixed ratio, fixed interval, and second order (fixed ratio embedded in fixed interval). |
Radioimmunoassay -
Performed cyclic AMP assay to assess efficacy of and dopamine and serotonin agonists. |
Rat Breathalyzer -
Developed an assay to sample and analyze breath ethanol levels in the rat. Involved in rat restraint design, rat training, and assay validation. |
Software Design -
Wrote novel software for operant behavior test chambers utilizing Med Associates MedPC system. Schedules written include: Fixed Interval, Fixed Ratio, Second Order, Progressive Ratio and Hand Training. |
in vivo Microdialysis -
Implanted bilateral guide cannulae (CMA/Microdialysis) targeting caudate or nucleus accumbens in squirrel monkeys. Performed experiments monitoring neurotransmitter levels in the caudate of awake squirrel monkeys. |
Journal Article |
| McMahon LR, Ginsburg BC, Lamb RJ. Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice Psychopharmacology (Berl) 2008 Jul;198(4):487-495.
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| Ginsburg BC, Javors MA, Friesenhahn G, Frontz M, Martinez G, Hite T, Lamb RJ. Mouse breathalyzer Alcohol Clin Exp Res 2008 Jul;32(7):1181-1185.
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| Lamb RJ, Ginsburg BC. Reinforcement magnitude modulates the rate-dependent effects of fluvoxamine and desipramine on fixed-interval responding in the pigeon Behav Pharmacol 2008 Feb;19(1):51-60.
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| Ginsburg BC, Martinez G, Friesenhahn G, Javors M, Lamb RJ. Acute tolerance to rate-decreasing effects of single doses of ethanol Physiol Behav 2008 Feb;.
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| McMahon LR, Ginsburg BC, Lamb RJ. Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice Psychopharmacology 2008 Jan;198:487-495.
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| Ginsburg BC, Lamb RJ. Taurine and ethanol interactions: behavioral effects in mice Eur J Pharmacol 2008 Jan;578(2-3):228-237.
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| Ginsburg BC, Lamb RJ. Fluvoxamine effects on concurrent ethanol- and food-maintained behaviors Exp Clin Psychopharmacol 2006 Nov;14(4):483-492.
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| Ginsburg BC, Lamb RJ. Effects of chronic fluvoxamine on ethanol- and food-maintained behaviors Life Sciences 2006 Aug;79(13):1228-1233.
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| Ginsburg BC, Lamb RJ. Effects of chronic fluvoxamine on ethanol-and food-maintained behaviors Life Sciences 2006 Jan;79(13):1228-1233.
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| Ginsburg BC, Lamb RJ. Fluvoxamine effects on concurrent ethanol- and food-maintained behaviors Experimental and Clinical Psychopharmacology 2006 Jan;14(4):483-492.
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| Ginsburg BC, Lamb RJ. Cannabinoid effects on behaviors maintained by ethanol and food: a within-subjects comparison Behavioral Pharmacology 2006 Jan;17(3):249-257.
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| Javors MA, Ginsburg BC, Friesenhahn G, Lamb RJ. Rat Breathalyzer Alcoholism: Clinical and Experimental Research 2005 Oct;29(10):1853-1857.
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| Kimmel HL, Ginsburg BC, Howell LL. In vivo microdialysis in squirrel monkeys actively self-administering cocaine Synapse 2005 Jun;56(3):129-134.
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| Ginsburg BC, Kimmel HL, Carroll FI, Goodman MM, Howell LL. Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys Pharmacology Biochemistry and Behavior 2005 Mar;80(3):481-491.
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| Czoty PW, Ginsburg BC, Howell LL. Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys Journal of Pharmacology and Experimental Therapeutics 2005 Mar;300(3):831-837.
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| Ginsburg BC, Lamb RJ. Alphaxalone and epiallopregnanolone effects in ethanol discriminating rats (in press) Alcoholism: Clinical and Experimental Research 2005 Jan;.
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| Lamb RJ, Ginsburg BC. Fluvoxamine and desipramine on fixed-ratio responding: Effects of reinforcement magnitude Behavioral Pharmacology 2005 Jan;16(7):573-578.
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| Ginsburg BC, Koek W, Javors MA, Lamb RJ. Effects of fluvoxamine on a multiple schedule of ethanol- and food- maintained behavior in two rat strains Psychopharmacology 2005 Jan;180:249-257.
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Book Chapter |
| Ginsburg BC, Gerak LR, McMahon LR, Roache JD. Neurosteroids in alcohol and substance use. In: Ritsner MS, Weizman A. Neuroactive Steroids in Brain Function, Behavioral and Neuropsychiatric Disorders: Novel Strategies for Research and Treatment. New York, NY: Springer; 2008. p. 507-536.
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Abstract |
| Ginsburg BC, Friesenhahn G, Martinez G, Javors MA, Lamb RJ. Mouse Breathalyzer; 2007 Jul. (Research Society of Alcoholism).
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| Ginsburg BC. Addition of concurrently available food decreases the sensitivity of ethanol self-administration to disruption by fluvoxamine; 2007 Jun. (College for Problems of Drug Dependence).
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| Ginsburg BC, Lamb RJ. Cannabinoid antagonist effect son behaviors maintained by ethanol and food San Francisco, CA; 2006 Apr. (Experimental Biology 2006).
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| Ginsburg BC, McMahon LR. Discriminative stimulus effects of 9-THC in C57BL/6J mice; 2006 Jan. (College on Problems of Drug Dependence).
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| Ginsburg BC, Lamb RJ. Selective effects of fluvoxamine on ethanol self-administration depend on the conditions of food availability; 2005 Mar. (Annual Meeting of the Texas Research Society on Alcoholism, San Antonio, TX).
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| Ginsburg BC, Lamb RJ. Differential ethanol-like discriminative stimulus of the neuroactive steroids alphaxalone and epiallopregnanolone; 2004 Jun. (27th Annual Meeting of the Research Society on Alcoholism, Vancouver, BC, Canada).
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| Ginsburg BC, Lamb RJ. Differential ethanol-like discriminative stimulus of the neuroactive steroids alphaxalone and epiallopregnanolone; 2004 Mar. (Annual Meeting of the Texas Research Society on Alchololism, Fort Worth, TX).
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Not Specified |
| Ginsburg BC, Lamb RJ. Cannabinoid effects on behaviors maintained by ethanol or food: a within-subjects comparison Behav Pharmacol 2006 May;17(3):249-257.
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